Truly resistant hypertension?

Truly refractory hypertension.

W hat really is refractory or resistant hypertension? Twenty years ago, Setaro and Black defined the condition as blood pressure >140/90 mm Hg, no evidence of secondary hypertension, maximal doses of at least 2 appropriate antihy-pertensive agents, and sufficient treatment duration to allow the treatments to be effective. 1 Today, we would probably expand the definition to at least 3 agents 2 o...

Residual effect of renal denervation in patients with truly resistant hypertension.

Resistant Hypertension

High blood pressure (BP) is the leading risk factor for premature death and disability-adjusted life years in the world. The development of a large pharmaceutical base from which to manage patients with hypertension in addition to many patient years of clinical trial experience have made it possible to successfully manage many of these patients. Nonetheless, many questions remain, particularly ...

Resistant hypertension.

Recent clinical trials suggest that resistant hypertension is increasingly common. In the majority of patients, uncontrolled hypertension is due to persistent elevation of the systolic blood pressure. Older age and obesity are associated with poor blood pressure control. Other contributing factors include severity of the underlying hypertension and renal insufficiency. Poor patient adherence is...

Resistant Hypertension

High blood pressure (BP) is the leading risk factor for premature death and disability-adjusted life years in the world. The development of a large pharmaceutical base from which to manage patients with hypertension in addition to many patient years of clinical trial experience have made it possible to successfully manage many of these patients. Nonetheless, many questions remain, particularly ...